Microfluidic Recirculation Pack

Cell culture is considered the foundation of many areas of cell biology research, including studies of cellular metabolism, gene expression, and signal transduction. Recently, a new field called organ-on-a-chip (OOAC) has begun to emerge, seeking to mimic the structure and function of organs using microfluidic cell culture systems. The goal of OOAC technology is to create miniature versions of human organs that can be used to study diseases, drug interactions, and toxicology in a more realistic and precise way than traditional cell culture or animal models. This allows for the production of in-vitro models reproducing physiologically relevant features observed in-vivo.

In order to maintain a cell culture or an OOAC system alive and functional over a long period of time, and due to the low volume contained in a microfluidic channel, recirculation is mandatory. It allows for constant provision of nutrients to the cells and application of a constant shear-stress, which is of primary importance for organ-on-chip technologies.

Our Microfluidic Recirculation Pack offers the ability to provide cells with a continuous flow, thereby controlling the transport of nutrients and the active mechanical constraints applied in the channel.