Microfluidic cell culture chip

Perform 2D culture experiments under flow, controlling mechanical shear stress on the cells in two independent channels. 

BE-Flow is the ideal device for research on the effect of flow and mechanical stress on a cell culture. Some of the most common applications include mechanical shear stress studies, interstitial flow on 3D cultures, rolling and adhesion, or circulating particle experiments. 

Vascular research: Because the BE-flow microfluidic cell culture chip was designed for vascular research, some of the most common applications of the BE-Flow device are related to this field of knowledge. Endothelial vascular cells like HUVEC or HAEC are influenced by various forces in the human body due to blood flow. Using the BE-Flow, it is possible to precisely control shear stress and transmural pressure at the same time. These forces play an important role in the gene expression of HUVEC cells and their proper development. In addition, these forces can be modified to a disease level to study phenomena such as thrombosis, atherosclerosis or rolling adhesion of circulating particles in the endothelial tissues.