Development of an in-vitro eye model with the Flow EZ
Development on an in-vitro model to estimate mass transfer from the anterior cavity
๐ข A new research paper by Tianyang Liu and colleagues from the ๐ข๐ฝ๐๐ฐ๐ฒ๐๐๐ถ๐ฐ๐ ๐๐๐ฑ, UCL School of Pharmacy and the National Institute for Health Research, London, UK, describes a ๐ป๐ฒ๐ ๐ถ๐ป-๐๐ถ๐๐ฟ๐ผ ๐ฒ๐๐ฒ ๐บ๐ผ๐ฑ๐ฒ๐น to estimate mass transfer through the iris/lens barrier in the case of drug intracameral injection.
๐ https://www.frontiersin.org/articles/10.3389/fddev.2022.1025029/full
The article relies on the ๐ถ๐บ๐ถ๐๐ฎ๐๐ถ๐ผ๐ป ๐ผ๐ณ ๐ถ๐ป-๐๐ถ๐๐ผ ๐ฐ๐ผ๐ป๐ฑ๐ถ๐๐ถ๐ผ๐ป๐ by reproducing several eye movements and perfusing the system at physiological flow-rates using ๐๐น๐๐ถ๐ด๐ฒ๐ป๐โ๐ ๐๐น๐ผ๐ ๐๐ญ, ๐๐๐ฃ๐ ๐ฃ๐น๐๐, ๐๐๐ก๐, ๐๐๐๐ฃ๐ง, ๐๐น๐ผ๐ ๐จ๐ป๐ถ๐ ๐ฆ ๐ฎ๐ป๐ฑ ๐๐ผ๐ณ๐๐๐ฎ๐ฟ๐ฒ.